Rotavirus gastroenteritis as a precipitating factor of celiac crisis in infancy: Case reports and review of literature

Introduction. Celiac crisis is a rare and life-threatening complication of celiac disease. Although it occurs in all ages, the most common affects children within first two years. Outline cases. We report three infants (two female, one male, age range 9?12) with crises as an initial presentation disease precipitated rotavirus gastroenteritis. was preceded by failure to thrive caused anorexia, occasional vomiting frequent abundant stools for 4?8 weeks, 1?2 days before admission fever, profuse watery diarrhea. They were admitted very severe general condition, severely dehydrated, markedly malnourished, enormously distended abdomen, edema lower legs feet, perianal erythema. After correction dehydration hypoalbuminemia, they placed on gluten- disaccharide-free diet weeks additional parenteral nutrition. The applied therapeutic measures resulted stabilization further rapid improvement patient?s condition. In patients latex agglutination test positive, IgA anti-TTG antibodies elevated (58.6?78 U/ml) homozygous carriers HLA DQ2 gene. Enterobiopsy performed after total villous atrophy (Marsh IIIc) registered patients. course, complete recovery patient accomplished strict gluten-free diet. Conclusion. Our experience indicates that gastroenteritis timely unrecognized classical can lead crisis.